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Related post: 1)Binds penicillin-binding proteins 2) Blocks transpeptidase cross- linking of cell wall 3) Activates autolytic enzymes
MOA: Dexamethasone Eye Drop Bactericidal antibiotics
Penicillin, Cephalosporins, Vancomycin, Aminoglycosides, Fluoroquinolones, Metronidazole
MOA: Block cell wall synthesis by Neomycin Polymyxin Dexamethasone inhib. Peptidoglycan cross-linking (7)
Penicillin, Ampicillin, Ticarcillin, Dexamethasone 4mg Pipercillin, Imipenem, Aztreonam, Cephalosporins
MOA: Block DNA topoisomerases
Quinolones
MOA: Block mRNA synthesis
Rifampin
MOA: Block nucleotide synthesis
Sulfonamides, Trimethoprim
MOA: Block peptidoglycan synthesis
Bacitracin, Vancomycin
MOA: Block protein synthesis at 30s subunit
Aminoglycosides, Tetracyclines
MOA: Block protein synthesis at 50s subunit
Chloramphenicol, Erythromycin/macrolides, Lincomycin, Clindamycin, Streptogramins Tobramycin Dexamethasone Ophthalmic (quinupristin, dalfopristin)
MOA: Disrupt Dexamethasone Ophthalmic Drops bacterial/fungal cell Dexamethasone 4 Mg membranes
Polymyxins
MOA: Unkown
Pentamidine
MOA:Disrupt fungal cell membranes
Amphotericin B, Nystatin, Fluconazole/azoles
Name common Polymyxins
Polymyxin B, Polymyxin E
Name several common Macrolides (3)
Erythromycin, Azithromycin, Clarithromycin
Name some common Sulfonamides (4)
Sulfamethoxazole (SMZ), Sulfisoxazole, Triple sulfas, Sulfadiazine
Name some common Tetracyclines (4)
Tetracycline, Doxycycline, Demeclocycline, Minocycline
Name the common Iv Dexamethasone Aminoglycosides (5)
Gentamicin, Neomycin, Amikacin, Tobramycin, Streptomycin
Name the common Azoles
Fluconazole, Ketoconazole, Clotrimazole, Miconazole, Dexamethasone Eye Itraconazole
Name the common Fluoroquinolones (6)
Ciprofloxacin, Norfloxacin, Ofloxacin, Dexamethasone Tablets Grepafloxacin, Enoxacin, Nalidixic acid
Name the common Non-Nucleoside Reverse Transcriptase Inhibitors
Nevirapine, Delavirdine
Name the common Nucleoside Reverse Transcriptase Inhibitors
Zidovudine (AZT), Didanosine (ddI), Zalcitabine (ddC), Stavudine (d4T), Lamivudine (3TC)
Name the Protease Inhibitors (4)
Saquinavir, Ritonavir, Indinavir, Nelfinavir
Name two classes of drugs Dexamethasone Price for HIV therapy
Protease Inhibitors and Reverse Transcriptase Inhibitors
Name two organisms Vancomycin is commonly used for?
Staphlococcus aureus and Clostridium difficile (pseudomembranous colitis)
Oral Penicillin
V
Resistance mechanisms for Aminoglycosides
Modification via Acetylation, Adenylation, or Phosphorylation
Resistance mechanisms for Cephalosporins/Penicillins
Beta-lactamase cleavage of Beta-lactam Dexamethasone Oral ring
Resistance mechanisms for Chloramphenicol
Modification via Acetylation
Resistance mechanisms for Macrolides
Methylation of rRNA near Erythromycin's ribosome binding site
Resistance mechanisms for Sulfonamides
Altered bacterial Dihydropteroate Synthetase, Decreased uptake, Dexamethasone Table or Dexamethasone Treatment Increased PABA synthesis
Resistance mechanisms for Tetracycline
Decreased uptake or Increased transport out of Dexamethasone Iv cell
Resistance mechanisms for Vancomycin
Terminal D-ala of cell Dexamethasone 5 Mg wall replaced with D-lac; Decreased affinity
Side effects of Isoniazid (INH)?
Hemolysis (if G6PD deficient), Neurotoxicity, Hepatotoxicity, SLE-like syndrome
Specifically, how does Foscarnet inhibit viral DNA pol?
Binds to the Pyrophosphate Dexamethasone Eye Drops Binding Dexamethasone 0.5 Site of the enzyme
The MOA for Chloramphenicol is ���������������..?
Inhibition of 50S peptidyl transferase, Dexamethasone Ophthalmic Ointment Bacteriostatic
Toxic effects of TMP include���������?
Megaloblastic anemia, Leukopenia, Granulocytopenia
Toxic side effects Dexamethasone Suspension of Oral Dexamethasone the Azoles?
Hormone synthesis inhibition (Gynecomastia), Liver dysfunction (Inhibits CYP450), Fever, Chills
Toxicities associated with Acyclovir?
Delirium, Tremor, Nephrotoxicity
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